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Tenvir EM is taken orally once a day, at the same time every day, with or without food. Because Buy Tenvir EM can cause renal impairment, patients with a creatinine clearance of 30 to 49 ml/min should only take one tablet every 48 hours, and patients with a creatinine clearance of less than 30 ml/min should not take Tenvir EM at all.